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What is Combigan used for?

Combigan (Brimonidine Tartrate, Timolol Maleate ophthalmic solution) is used to manage ocular hypertension (high pressure in the eye) caused by eye diseases including open angle glaucoma. Ocular hypertension can lead to eye pain and potentially blindness if left untreated.

Combigan helps the eye remove excess liquid as part of it’s regular function. High pressure pressure can occur when fluids remain in the eye instead of flowing out as intended. It also decreases the amount of fluid produced in the eye to prevent symptoms.

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    Frequently Asked Questions About Combigan

    How to Use Combigan?

    Before you start taking Combigan, and after every refill, carefully read and follow the instructions provided in the drug information material included with the product. If the instructions are unclear, or if you have any questions, call your doctor or pharmacist as proper use will provide the maximum benefit. They can provide medical advice including warnings and precautions.

    If you wear contact lenses, they should be removed before taking combigan. Soft contact lenses can absorb the medication from the solution. Do not put them back in for 15 minutes after taking your dose.

    Wash your hands with water before handling the bottle or dropper. Do not let the dropper touch any surfaces to prevent contamination. It does not need to be washed between doses. You can simply put the cap back on the bottle

    If you need a different eye drop to manage symptoms, wait at least 10 minutes before using a different eye medication. Do not use Combigan if you have chronic obstructive pulmonary disease (COPD) as it can worsen your condition. You may need to use a different drug to treat glaucoma or ocular hypertension.

    This is not meant to be used by children under 2 years of age due to a risk of side effects that are mild to adults but potentially serious in children. If you are pregnant, or plan to become pregnant, inform your doctor to determine if Combigan can contaminate breast milk.

    What are Side Effects of Combigan?

    Combigan has known side effects. This is not a complete list and includes frequently reported adverse events. If you experience any signs and symptoms of serious side effects when taking Combigan, talk to your doctor or seek emergency care.

    Report side effects with Combigan to your doctor. If you find them unmanageable call your doctor for medical advice about side effects.

    • slow, fast, or irregular heartbeat
    • difficulty breathing
    • lack or loss of strength
    • loss of interest or pleasure
    • Chest pain or discomfort
    • trouble concentrating
    • stopping of heart
    • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
    • sensitivity of the eyes to light
    • headache
    • dizziness
    • trouble sleeping
    • feeling of having something in the eye
    • unconsciousness
    • feeling sad or empty
    • sleepiness or unusual drowsiness
    • noisy breathing
    • watery eyes
    • nervousness
    • disturbed color perception
    • tightness in the chest
    • Burning, dry, or itching eyes
    • halos around lights
    • discharge or excessive tearing
    • pounding in the ears
    • tunnel vision
    • Blurred or loss of vision
    • cough
    • stinging in the eyes
    • double vision
    • Dry mouth
    • lightheadedness, dizziness or fainting
    • night blindness
    • lack of appetite
    • tiny bumps on lining of the eyelid
    • irritability
    • no blood pressure or pulse

    Combigan Drug Interactions

    The following drugs are known to interact with Combigan. This is not an exhaustive list of all possible drug interactions. It is important to disclose all your current medications, (including prescription medications and herbal products) with your doctor to prevent allergic reactions or adverse interactions. They may have to determine if the interaction is worth the benefit of using both drugs or if your therapeutic plan needs to be changed.

    • Tolfenamic Acid
    • Diclofenac
    • Linagliptin
    • Formoterol
    • Methyldopa
    • Proquazone
    • Tamsulosin
    • Lixisenatide
    • Albuterol
    • Dronedarone
    • Metildigoxin
    • Tenoxicam
    • Piroxicam
    • Albiglutide
    • Clonixin
    • Tolazamide
    • Acemetacin
    • Salsalate
    • Canagliflozin
    • Phentolamine
    • Felbinac
    • Oxaprozin
    • Iohexol
    • Diflunisal
    • Olodaterol
    • Miglitol
    • Diltiazem
    • Cimetidine
    • Empagliflozin
    • Oxyphenbutazone
    • Sodium Salicylate
    • Rivastigmine
    • Naproxen
    • Insulin Glargine, Recombinant
    • Clonidine
    • Tiaprofenic Acid
    • Digoxin
    • Phenoxybenzamine
    • Oxymetazoline
    • Tolbutamide
    • Acarbose
    • St John's Wort
    • Aceclofenac
    • Rofecoxib
    • Fenoldopam
    • Choline Salicylate
    • Insulin Lispro, Recombinant
    • Terazosin
    • Levalbuterol
    • Epinephrine

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    DISCLAIMER: The information provided here is for informational purposes only and is not intended to replace the medical advice provided by a certified medical professional. Any prescription drug use needs to be approved by your doctor. Do not avoid or ignore any advice provided by your physician in favor of what is written here. Always consult with a pharmacist or doctor before taking this medication and seek counselling if you have any questions or concerns about your medication.