What is Mesalazine used for?
Octasa is prescribed to treat ulcerative colitis and helps reduce symptoms of ulcerative colitis like rectal bleeding, stomach pain, and diarrhea. Octasa is an aminosalicylate which works by decreasing swelling in the colon.
This section contains uses of Octasa that are not listed in the approved professional labelling for the drug that your doctor might prescribe. Use Octasa for this condition only if prescribed by your doctor. Octasa can be used for Crohn’s disease.

Mesalazine (Octasa / Asacol) Information
How to Use Octasa?
Take Octasa by mouth either with or without food as told by your doctor, usually 3 times per day. Never crush, break, or chew Octasa as this will affect the medication’s release into the colon. Your individual dosage will be based on your response to treatment and healthcare needs. Different brands of Octasa will deliver different amounts of the medication so don’t switch brands unless your doctor approves. Ensure you take Octasa at the same time daily to help you remember to consistently use it.
Octasa Drug Interactions
There are some medications that should never be used together even though there are some cases in which two medications can be used together despite interacting. In these cases your doctor may adjust the dose of one or both medication or they might take other precautions. This list is not exhaustive so always tell your doctor about all the medications you use so that your doctor can properly monitor for interactions.
Using Octasa together with the following medications is not typically recommended but could be required some times. In a situation where both medications are prescribed, your doctor might adjust the dosages or the timing of use for these medications.
- Mercaptopurine
- Varicella Virus Vaccine
Octasa being used in combination with the following medications can cause an increase in the risk of side effects, but using both medications could be the best treatment for you.
- Tamarind
- Warfarin