What is Xigduo XR used for?
Xigduo XR It contains the active ingredients dapagliflozin and metformin; two drugs used in the treatment of type 2 diabetes. By combining two different drugs, Xigduo XR controls blood glucose levels by using various mechanisms. Dapagliflozin increases the amount of glucose being removed by the kidneys. Metformin increases your body’s response to insulin, treats high blood sugar (hypoglycemia) made by the liver and decreases the amount of glucose absorbed through the stomach and intestines.
Xigduo XR Information
Always read and understand the patient information guide provided with the product before you begin taking Xigduo XR. When you buy Xigduo XR online from Your Canada Drug Store, we always send the products in the manufacturer’s packaging.
Xigduo XR is an extended release formulation intended for once daily dosing. Xigduo XR should be taken by mouth once daily in the morning with breakfast.
The tablet should be swallowed whole and should not be crushed or chewed. Damaging the tablet will damage the extended release formulation of the tablet and cause the release of all the drug at once instead of in a time release manner. This can lead to an increase in side effects.
Xigduo XR should be taken everyday along with diet and exercise to obtain the most benefit in controlling blood glucose levels. You may also need to take sulfonylureas or insulin to get the best results. It can also reduce your risk of hospitalization for heart failure.
In rare instances, metformin, one of the medicines in Xigduo XR, can build up in the body and cause lactic acidosis (build up of lactic acid in the blood). This is more likely in older persons with liver or kidney disease, persons with heavy alcohol use, and in persons who have had an X-ray using iodinated contrast. You should stop taking Xigduo XR and be treated in a hospital if you experience lactic acidosis.
Some symptoms and signs of lactic acidosis are stomach pain with nausea/vomiting/diarrhea, unusual tiredness, slow/irregular heartbeat, dizziness, blue/cold skin, severe drowsiness, fast/difficult breathing, chills or muscle pain.
A rare bacterial infection (necrotizing fasciitis) may occur near the anus and genitals during treatment. Seek medical attention and call your healthcare provider if these conditions occur. Inform your doctor if you experience symptoms of low blood.
The following drugs are known to interact with Xigduo XR. This is not an exhaustive list of all possible drug interactions. It is important to disclose all your current medications, (including prescription medications and herbal products) with your doctor to prevent allergic reactions or adverse interactions. They may have to determine if the interaction is worth the benefit of using both drugs or if your therapeutic plan needs to be changed.
- Metrizoic Acid
- Iodohippuric Acid
- Iopronic Acid
- Ioxitalamic Acid
- Ioglycamic Acid
- Acetrizoic Acid
- Thioctic Acid
Xigduo XR has known side effects. This is not a complete list and includes frequently reported adverse events. If you experience any signs and symptoms of serious side effects when taking this, talk to your doctor or seek emergency care.
Report side effects to your doctor. If you find them unmanageable call your doctor for medical advice about side effects. We also have a pharmacist that can provide counselling when you buy Xigduo XR online.
- difficulty having a bowel movement
- fast, shallow breathing
- voice changes
- sore throat
- Bladder pain
- cold sweats
- frequent urge to urinate
- troubled swallowing
- pain, tenderness, redness, or swelling of the area between the anus and genitals
- lower back or side pain
- change in the color, amount, or odor of vaginal discharge
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- difficult, burning, or painful urination
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- unusual tiredness or weakness
- redness of the skin
- bloody or cloudy urine
- fast heartbeat
- increased hunger
- loss of consciousness
- joint pain, stiffness, or swelling
- cool, pale skin
- body aches or pain
- general feeling of discomfort
- Back pain
- slurred speech
- dark urine
- hives, itching, or rash in the face, lips tongue
- muscle pain or cramping
- vomiting of blood
- loss of appetite
- stuffy or runny nose
- yellow eyes or skin
- swelling of the eyelids, face, lips, hands, or feet
- stomach discomfort
- tightness in the chest
- blurred vision
- Muscle aches
- clay-colored stools
- tender, swollen glands in the neck
- unpleasant breath odor
- Decreased appetite
- swelling of the penis
Current discounts and promotions when you buy Xigduo XR online can be found here
DISCLAIMER: The information provided here is for informational purposes only and is not intended to replace the medical advice provided by a certified medical professional. You require your doctor's approval prior to buying or using prescription drugs sold here. We do have a pharmacist on staff if your doctor is unavailable to provide medical advice when you buy Xigduo XR online. Do not use the information here to ignore or contradict advice provided by a licensed medical professional. Always seek medical advice if you have any questions or concerns about this medication.