What is Vagifem (Estradiol Hemihydrate) used for?
Vagifem (estradiol vaginal inserts) is a female hormone medication used to reduce the symptoms of menopause in the Vagina. These symptoms include itching, a burning sensation, vaginal dryness and are caused by a lack of estrogen produced naturally by the body.
Vagifem is more effective for vaginal symptoms than other applications. It works directly in the vagina instead of being absorbed by other parts of the body. Do not share vagifem with friends and family that have similar symptoms.
Frequently Asked Questions About Vagifem (Estradiol Hemihydrate)
Before taking you start using vagifem, carefully read the product information/prescribing information leaflet and contact our doctor if you have any questions. Follow your doctor’s instructions as correct use will require the best results.
If the tablet falls out of the applicator, replace the tablet and use a new one to avoid contamination. Discard the applicator after use. Vagifem needs to be taken consistently to get the best results. If you forget to take a dose, take it when you remember.
If it is almost time for your next dose, skip the missed dose and continue with your schedule. Taking too much medication at one time increases your chance of experiencing side effects.
The following drugs are known to interact with Vagifem. This is not an exhaustive list of all possible drug interactions. It is important to disclose all your current medications, (including prescription medications and herbal products) with your doctor to prevent allergic reactions or adverse interactions. They may have to determine if the interaction is worth the benefit of using both drugs or if your therapeutic plan needs to be changed.
- St John's Wort
- Eslicarbazepine Acetate
- Valproic Acid
- Tranexamic Acid
- Mycophenolic Acid
Vagifem Has known side effects. This is not a complete list and includes frequently reported adverse events. If you experience any signs and symptoms of serious side effects when taking Vagifem, talk to your doctor or emergency care.
Report side effects with Vagifem to your doctor. If you find them unmanageable call your doctor for medical advice about side effects.
- swelling of eyelids, face, lips, hands, or feet
- thick, white vaginal discharge without odor or with a mild odor
- muscle pain
- unusual or unexpected vaginal bleeding after menopause
- trouble with breathing or swallowing
- rapid increase in height
- skin redness
- stinging or redness of the genital area
- tightness in the chest
- Breast pain
- vaginal burning or pain (with estradiol vaginal insert or ring)
- clear vaginal discharge (usually means the medicine is working)
- itching of the vagina or genitals
- joint pain, stiffness, or swelling
- growth of pubic hair
- swelling of the breasts or breast soreness in males
- enlargement of penis or testes
- fast heartbeat
- enlarged breasts
- Abdominal or back pain
- feeling faint
- shortness of breath
- Feeling of vaginal pressure (with estradiol vaginal insert or ring)
- fluid retention
- nausea and vomiting
DISCLAIMER: The information provided here is for informational purposes only and is not intended to replace the medical advice provided by a certified medical professional. Any prescription drug use needs to be approved by your doctor. Do not avoid or ignore any advice provided by your physician in favor of what is written here. Always consult with a pharmacist or doctor before taking this medication and seek counselling if you have any questions or concerns about your medication.