What is Tasigna used for?
Tasinga is used to treat newly diagnosed Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML) in chronic phase (CP). It is used to stop or slow the growth of cancer cells. Tasinga is used in adults and children at least one year of age. It may however affect growth and development of children. Doctor’s may consider this if other treatments have not proven effective. Do not share this medication with others as this may not be an effective treatment if not approved by a doctor.
Tasigna Information
How to Use Tasigna?
Before taking Tasigna for the first time carefully read the drug information provided for instructions on what side effects include. If you are unsure how to take it or how often, contact your medical professional or pharmacist to clarify.
Avoid grapefruit juice and grapefruit adjacent products as this can increase your risk of side effects. It is usually taken orally on an empty stomach twice a day in 12 hour intervals. The pill should not be chewed, split or crushed unless directed by your doctor.
If you are unable to swallow the capsule whole, you are able to mix it with applesauce and liquids. You should drink plenty of water while talking this and time your dose while considering other medications and meals. They can impact absorption.
Tasigna Drug Interactions
The following drugs are known to interact with Tasigna. This is not an exhaustive list of all possible drug interactions. It is important to disclose all your current medications, (including prescription medications and herbal products) with your doctor to prevent allergic reactions or adverse interactions. They may have to determine if the interaction is worth the benefit of using both drugs or if your therapeutic plan needs to be changed.
- Sodium Phosphate, Dibasic
- Donepezil
- Ozanimod
- Pimozide
- Iloperidone
- Ranolazine
- Lofexidine
- Mitotane
- Ibutilide
- Levofloxacin
- Cobicistat
- Nortriptyline
- Alfuzosin
- Warfarin
- Boceprevir
- Clozapine
- Triclabendazole
- Tolvaptan
- Omeprazole
- Telaprevir
- Poliovirus Vaccine, Live
- Mifepristone
- Salmeterol
- Pentamidine
- Eslicarbazepine Acetate
- Bosutinib
- Probucol
- Deutetrabenazine
- Aripiprazole
- Selpercatinib
- Pipamperone
- Sulpiride
- Encorafenib
- Ceritinib
- Clomipramine
- Chlorpromazine
- Mizolastine
- Apomorphine
- Osilodrostat
- Carbamazepine
- Amisulpride
- Sotalol
- Diltiazem
- Halofantrine
- Trifluoperazine
- Sertraline
- Rifabutin
- Dexlansoprazole
- Tramadol
- Sodium Phosphate, Monobasic
What are Side Effects of Tasigna?
Few known side effects of Tasigna:
- dark urine
- faster heart rhythm
- back pain
- rapid, shallow breathing
- joint pain or swelling
- muscle stiffness
- nervousness
- decreased appetite
- nausea
- sweating
- rapid weight gain
- diarrhea
- fainting
- headache
- sneezing
- dizziness
This is not a complete list and includes frequently reported adverse events. If you experience any signs and symptoms of serious side effects when taking Tasigna, talk to your doctor or emergency care.
Report side effects with Tasigna to your doctor. If you find them unmanageable call your doctor for medical advice about side effects.
Recommended dosage for Tasigna?
The recommended dosage of Tasigna (nilotinib) for most adult patients with newly diagnosed chronic phase chronic myeloid leukemia (CML) is
- 300 mg once daily.
For patients with resistant or intolerant CML in the chronic or accelerated phase, the usual dosage is:
- 400 mg once daily.
Always take Tasigna on an empty stomach, and avoid eating for at least 2 hours before and 1 hour after taking it.
It’s important to follow your doctor’s instructions for your specific situation.
Tasigna Price in Canada
Starting price of Tasigna 150mg Capsule price in Canada
- 112 capsules - $4227.65 USD ($37.75 per capsules)
Tasigna Coupon
Current discounts and promotions for Tasigna can be found here
Tasigna FAQs
What types of leukemia does Tasigna treat?
Tasigna (generic name: nilotinib) is used to treat a type of leukemia called Chronic Myeloid Leukemia (CML). Specifically, it is for patients who have the Philadelphia chromosome-positive (Ph+) form of CML. This means the leukemia cells have a specific genetic abnormality called the Philadelphia chromosome.
How is Tasigna different from other CML treatments?
Tasigna is different from other CML treatments because it’s often more effective at targeting leukemia cells and can lead to faster results. Additionally, Tasigna must be taken on an empty stomach, unlike some other CML medications that can be taken with food. It’s important to follow your doctor’s instructions for your specific condition.
Does Tasigna cause weight gain or loss?
Tasigna usually does not cause significant weight gain or loss. However, some people might experience changes in weight as a side effect. If you notice any unusual weight changes while taking Tasigna, it's a good idea to talk to your doctor.
Does Tasigna affect blood sugar levels?
Yes, Tasigna (nilotinib) can affect blood sugar levels. It may cause an increase in blood sugar, leading to hyperglycemia in some patients. If you are taking Tasigna, it's important to monitor your blood sugar levels, especially if you have diabetes or are at risk for developing it. Always inform your healthcare provider if you notice any changes in your blood sugar levels while on this medication.
How often do I need to see my doctor while on Tasigna?
Typically, you will need to visit your doctor every 2 to 4 weeks initially, but this may vary based on your specific situation and how you respond to the medication. Your doctor will monitor your health, check for side effects, and adjust your treatment as needed. Always follow your doctor’s recommendations for appointment frequency.
Can Tasigna be used in people with liver or kidney problems?
Tasigna should be used with caution in people with liver or kidney problems. It is not recommended for people with severe liver or kidney issues unless the doctor decides the benefits outweigh the risks. If you have liver or kidney problems, your doctor may need to monitor you closely during treatment. Always inform your doctor about any existing liver or kidney conditions before starting Tasigna, as adjustments to your treatment plan may be necessary.
What lifestyle changes should I make while on Tasigna?
While on Tasigna, you should make a few key lifestyle changes:
First, follow a healthy diet and avoid high-fat meals, as Tasigna can be affected by food. It's also important to avoid grapefruit and grapefruit juice, which can interfere with the medication.
Regular exercise and staying hydrated can help manage side effects. Lastly, avoid smoking and limit alcohol consumption, as these can impact your health and treatment effectiveness.
Always follow your doctor’s advice for any specific lifestyle changes.