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What is Spironolactone? What is Spironolactone used for?

Spironolactone (Aldactone) is usually used in conjunction with other medicines to manage high blood pressure (hypertension) and heart failure. High blood pressure can increase the risk of heart attack and stroke. When you take Spironolactone the need for hospitalization after heart failure is reduced. This medication is considered a diuretic which removes excess fluids and salt without lowering potassium levels. Edema (fluid retention) is common for those suffering from cirrhosis of the liver, nephrotic syndrome and congestive heart failure. Edema can result in uncomfortable swelling and puffiness. It can also be used to treat acne in women and prevent excessive hair growth in combination with oral contraceptives.

Different strengths and manufacturers will have different packaging.


When taking Spironolactone be sure to take it as directed by your doctor and with the instructions included with the packaging. It’s recommended to take your daily dose well before bedtime to avoid interruption of sleep to get up and use the bathroom. If you find this medication irritates your stomach it may help to take it with food. Your dosage may change depending on your response to treatment and your medical condition. Be mindful to take this around the same time daily to get the best possible results. Breakfast and lunch are ideal times if you eat at consistent times and will prevent nighttime urination. If you begin to feel better do not take Spironolactone as people with high blood pressure do not often report common “sick” feelings. Do not take this more often than prescribed as it will not accelerate treatment and may result in unwanted side effects. If you notice you experience increased blood pressure despite taking this routinely, contact your doctor.
Spironolactone has the following known side effects. This is not a complete list of all potential side effects. Mild side effects can be manageable and may even go away as you become accustomed to the medicine. Serious side effects may require immediate medical attention. If you need help managing the side effects contact your doctor for counselling.

  • sexual function problems
  • persistent nausea/vomiting
  • easy bruising/bleeding
  • severe stomach/abdominal pain
  • breast pain
  • increased thirst
  • vomit that looks like coffee grounds
  • yellowing of the eyes/skin
  • signs of kidney problems (such as change in the amount of urine)
  • mental/mood changes
  • menstrual period changes
  • signs of infection (e.g., fever, persistent sore throat)
  • dark urine
  • breast enlargement (gynecomastia) in men
  • muscle spasms
  • unusual fatigue/weakness
  • Inspra (Eplerenone) and other aldosterone receptor antagonists
  • ACE inhibitors, such as benazepril (Lotensin)
  • Digoxin (Lanoxin)
  • Potassium supplements
  • Skeletal muscle relaxers, including cyclobenzaprine (Amrix, Flexeril)
  • Norepinephrine
  • Angiotensin II receptor blockers, such as azilsartan (Edarbi)
  • Lithium (Eskalith, Lithobid)
  • Steroids such as prednisone
  • Heparin (Hemochron, Hep-Lock) and low-molecular-weight heparin (Lovenox)
  • Cholestyramine (Questran, Cholybar)
  • Other diuretics, such as amiloride (Midamor)
  • Ibuprofen (Advil) and other non-steroidal anti-inflammatory drugs
Spironolactone can be used to treat acne in women. It prevents testosterone from binding to the hair follicles that lead to acne. Talk to your doctor for counselling on whether this medication can treat your acne. .
This can be used to treat Female Pattern Hair Loss (FPHL). IT may also cause partial hair growth. This treatment is off label. Your doctor can provide medical advice if you need it.
Spironolactone is used to treat high blood pressure, water retention and acne.
There is no conclusive evidence to confirm Spironolactone affects your weight.
Spironolactone is a diuretic that removes excess fluid and salt in the body.
Spironolactone reduces the amount of water and salt without losing potassium. This helps lower blood pressure and treats edema.


DISCLAIMER: The following is provided exclusively to provide general information to help those who want to buy spironolactone online and is not intended as a substitute for professional medical advice. Always seek out a physician or other licensed health care provider’s advice for your medical condition or treatment plan. Do not ignore professional advice or delay seeking it out because of the information provided here.