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HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
ESTROGENS – ORAL (ES-troe-jenz)
Common Brand Name(s)
COMMON BRAND NAME(S): Congest, Estrace, Premarin
Estrogens, used either with another hormone (progestin) or alone have rarely caused serious side effects. Discuss benefits and risks of hormone treatment with your doctor. Estrogens are not to be used to prevent dementia or heart disease. They can increase the risk of uterine cancer. Taking progestin as directed by your doctor can help mitigate that risk. If you have any unusual vaginal bleeding tell your doctor immediately. In women who are postmenopausal estrogens can increase the risk of ovarian cancer, dementia, serious blood clots in the legs and stroke. When used for up to 7 years estrogens alone do not seem to increase the risk of breast cancer. When used with a progestin they can increase the risk of stroke, blood clots, dementia, risk of heart disease, and cancer of the ovaries/breast. The side effect risk may depend on the length of time it’s used for and dosage of estrogen. This medication should be used for the shortest amount of time at its lowest effective dose. Discuss this medication with your doctor regularly to see if you still need to use it. If you will continue usage for a long time have physicals as directed by your doctor.
This medication is a female hormone used by women to help in reducing menopause symptoms. These symptoms can be caused by the body making less estrogen. If you use this medication only for symptoms around the vaginal area products applied directly inside the vagina should be considered before an oral, injected, or absorbed through the skin medication. This medication can also be used by women who don’t naturally produce enough estrogen. Some estrogen products can be used post menopause to prevent osteoporosis however, other medications are also effective in preventing bone loss and can be safer. Consider these medications before estrogen treatment.
How to Use
Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor. You may take it with food or right after a meal to prevent stomach upset. If you are taking the extended-release tablets, do not crush, chew, or dissolve them. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. The dosage is based on your medical condition and response to treatment. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day as directed. Follow your dosing schedule carefully. Do not increase your dose or take this medication more often or for a longer time than directed. Tell your doctor if your condition does not improve or if it worsens.
Nausea/vomiting, breast tenderness, bloating, weight changes or headache may occur, if they persist/get worse tell your doctor. Your doctor has assessed the risks and prescribed the medication as they believe the benefits outweigh the risks. Most people never experience serious side effects. however if you experience any of the following tell your doctor immediately: increased or new vaginal irritation/itching/odor/discharge, severe stomach/abdominal pain, persistent nausea/vomiting, mental/mood changes , breast lumps, unusual vaginal bleeding, increased thirst/urination, yellowing eyes/skin, dark urine, swelling hands/ankles/feet. Rarely this medication can cause serious problems from blood clots. If you have any of these serious side effects seek medical attention: unusual sweating, severe/sudden headache, jaw/left arm/chest pain, confusion, slurred speech, sudden vision changes, weakness on one side of the body, redness/pain/swelling of legs, numbness/tingling/weakness in the arms/legs, coughing up blood, sudden fainting/dizziness, trouble breathing. Serious allergic reactions to this product are rare, however if any of the following occur get medical attention: itching/swelling, rash, trouble breathing, severe dizziness. These are not all of the possible side effects, if other symptoms present themselves talk to your doctor immediately.
Tell your doctor or pharmacist if you’re allergic to Premarin or of any allergies, there may be inactive ingredients in this medication that can cause allergic reactions or other issues. Tell your doctor and pharmacist of your medical history including: certain cancers, vaginal bleeding of unknown cause, stroke, heart disease, blood clots, kidney disease, liver disease, family medical history, swelling disorder, blood clotting disorder, diabetes, high cholesterol/triglyceride levels, lupus, obesity, high blood pressure, mineral imbalance, underactive thyroid, uterus problems, seizures, asthma, hormone problems, , migraine headaches, mood/mental disorder. Do not smoke or use tobacco. Estrogens in combination with smoking can increases risk of blood clots, high blood pressure, heart attack or stroke especially in women over 35. If you are having surgery or will be confined to a chair for a long period of time tell your doctor as this can cause blood clots. this medication can cause dark areas on your face and skin, sunlight or tanning will make this worse. If you’re wearing contact lenses or are nearsighted you may develop vision problems, if this occurs contact your eye doctor. This medication must not be used when pregnant. Consult with your doctor before breast-feeding as this medication can pass into breast milk and reduces the quality and amount of breast milk.
Interactions with medication can change how your medications work or can increase the chances of serious side effects. This is not a full list of all possible interactions, keep a list of the products you use and share them with your doctor and pharmacist. Products that can interact with this drug include: fulvestrant, raloxifene, tamoxifen, fulvestrant, aromatase inhibitors, tranexamic acid. This medication can cause false results in lab tests so make sure lab personnel and your doctors know you use this medication.
If someone is having trouble breathing or has passed out they may have overdosed, call 911 or poison control immediately.
This medication is not to be shared with others. Keep laboratory and medical appointments to monitor your progress and monitor for side effects. Follow instructions from your doctor about self breast exams and report lumps right away. Preventing and controlling high blood pressure, diabetes and high cholesterol can help reduce chances of stroke or heart attack. Prevent dementia with mental exercises to keep your mind active. Talk to your doctor about lifestyle changes that can help reduce hot flashes, and promote healthy bones.
If you forget a dose use it as soon as you remember unless it’s near the time of the next dose. Do not double up doses to catch up.
Store at room temperature, do not store in the bathroom, keep away from pets and children. Only dispose of medications as directed by a pharmacist or waste disposal company.