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HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
ALIROCUMAB – SUBCUTANEOUS INJECTION (AL-i-ROK-ue-mab)
Common Brand Name(s)
COMMON BRAND NAME(S): Praluent
Praluent (Alirocumab) is used along with a proper diet and maximally tolerated “statin” drugs to help lower “bad” cholesterol (LDL) in the blood. It is used by people who have an inherited condition that causes high levels of LDL or who have blockage in the heart blood vessels, who need more lowering of LDL levels. Alirocumab belongs to a class of drugs known as monoclonal antibodies. It works by improving how well your body gets rid of LDL cholesterol. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.
How to Use
Read the Patient Information Leaflet and Instructions for Use provided by your pharmacist before you start using alirocumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Before use, take alirocumab out of the refrigerator and let it warm up to room temperature for 30 to 40 minutes. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. If needed, this medication may be kept in the original package at room temperature for up to 30 days. Do not shake this medication.
Redness, itching, swelling, or pain at the injection site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. A very serious allergic reaction to this drug is rare.
Before using alirocumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Do not share this medication with others. Lab and/or medical tests (such as LDL cholesterol levels) should be done while you are using this medication. Keep all medical and lab appointments.
If you are using this medication every 2 weeks and miss a dose, use it as soon as you remember if it is within 7 days after the missed dose. If it is longer than 7 days from the missed dose, skip the missed dose. Use your next dose at the regular time.
Store in the refrigerator away from light and moisture. Do not freeze. If needed, this medication may be kept at room temperature. If stored at room temperature, keep it in the original package and use within 30 days. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.