Onglyza

Onglyza

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Onglyza (Saxagliptin Hydrochloride)

DISCLAIMER: This is a summary and doesn’t contain all possible information about Onglyza. It is intended to educate consumers and does not replace medical advice from a licensed professional. This information does not guarantee that this is a safe, appropriate, or effective product for you. Always ask a health care professional for information regarding your treatment and medications.

Onglyza (saxagliptin) is used in combination with a proper diet and exercise program to control high blood sugar in those with type 2 diabetes. You can control high blood sugar to help prevent blindness, kidney damage, sexual function problems, loss of limbs, nerve problems. Controling diabetes can also lessen your risk of a stroke or heart attack. Saxagliptin works by increasing the levels of incretins, a natural substance in your body that increases insulin release to help control blood sugar, especially after a meal. They also decrease the amount of sugar made by your liver.

Always read the medication information provided when you buy Onglyza and when you get a refill. Take saxagliptin orally, with or without food, as directed by your doctor, usually once a day. The manufacturer instructs that the tablet should not be split/cut before you take it. However, there are many similar medications (immediate-release tablets) that can be cut or split. Follow your doctor’s directions on how to best take the medication.

Your dosage will be based on your medical condition, other medications you might be taking and your response to treatment. Take Onglyza regularly to get the full effects, take it at the same time daily to help you remember. Always follow your doctor’s instructions for all of the medications you take.

Drug interactions can affect how your medications work or increase the risk of serious side effects. This is not a complete list of all potential drug interactions. Keep a list of all the products you use including non-prescription, prescription, and herbal products and tell your doctor about them so that they can monitor closely for drug interactions. Do not change, start, or stop any medications without your doctor knowing.

There may be interactions with the following products:

If you have any questions about medications that can interact with Onglyza you can reach out to our customer service team at 1-844-416-4282 and request to speak to one of our licensed pharmacists.

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Along with the needed effects of Onglyza, it may also lead to unwanted side effects. Though not all of these side effects will occur, if they do, you may need medical attention. 

If you encounter any of the following side effects check with your doctor immediately: 

More common

  • Anxiety
  • Bladder pain
  • Bloating or swelling of the hands, arms, feet, face, hands, or lower legs. 
  • Bloody or cloudy urine
  • Blurred vision
  • Body aches or pain
  • Chills 
  • Cold sweats
  • Confusion 
  • Cool, pale skin
  • Cough 
  • Depression 
  • Difficult, burning, or painful urination
  • Difficulty with breathing
  • Dizziness 
  • Ear congestion
  • Fast heartbeat
  • Fever 
  • Frequent urge to urinate
  • Headache 
  • Increased hunger
  • Loss of voice
  • Lower back or side pain
  • Nasal congestion
  • Nausea 
  • Nightmares 
  • Rapid weight gain
  • Runny nose
  • Seizures 
  • Shakiness 
  • Slurred speech
  • Sneezing 
  • Sore throat
  • Tingling of the hands or feet
  • Unusual tiredness or weakness
  • Unusual weight gain or loss

Incidence not known

  • Chest pain
  • Constipation 
  • Darkened urine
  • Decreased urine output
  • Difficulty with swallowing
  • Dilated neck veins
  • Extreme fatigue
  • Flaking or peeling of the skin
  • Hives or skin rash
  • Indigestion 
  • Irregular breathing
  • Irregular heartbeat
  • Large, hive-like swelling on the lips, tongue, eyelids, face, sex organs, feet, tongue, hands, or throat
  • Loss of appetite
  • Pains in the stomach, side, or abdomen, possibly radiating to the back
  • Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • Severe joint pain
  • Swelling of face, fingers, feet, or lower leg
  • Tightness in the chest
  • Troubled breathing
  • Vomiting 
  • Weight gain
  • Yellow eyes or skin

You may encounter some side effects that don’t usually require medical attention. These side effects are mild and will usually go away as your body adjusts to the new medication. Your doctor may also be able to tell you about other ways to prevent or reduce some of these side effects. Check in with your doctor if the following effects persist or are bothersome: 

Less common

  • Diarrhea
  • Pain or tenderness around the eyes and cheekbones
  • Redness of the skin
  • Weakness 
  • Welts 

Some patients may experience side effects that are not listed here. If you notice any of those other effects check in with your healthcare professional.

SAXAGLIPTIN – ORAL